Huperziawuhlobo lobulembu obumila eShayina. Ihlobene ne-club mosses (umndeni we-Lycopodiaceae) futhi yaziwa kwezinye izazi zezitshalo ngokuthi i-Lycopodium serratum. I-moss yonke elungisiwe yayisetshenziswa ngokwesiko. Amalungiselelo amakhambi esimanje asebenzisa kuphela i-alkaloid engayodwa eyaziwa ngokuthi i-huperzine A. I-Huperzine A iyi-alkaloid etholakala ku-huperzia okuye kwabikwa ukuthi ivimbela ukuwohloka kwe-acetylcholine, into ebalulekile edingwa isimiso sezinzwa ukuze sidlulisele ulwazi kusuka kungqamuzana ukuya kungqamuzana. Ucwaningo lwezilwane luphakamise ukuthi i-huperzine A'Ikhono lokulondoloza i-acetylcholine lingase libe likhulu kuneleminye imithi kadokotela. Ukulahlekelwa umsebenzi we-acetylcholine kuyisici esiyinhloko sezinkinga eziningana zokusebenza kobuchopho, kuhlanganise ne-Alzheimer's isifo. I-Huperzine A ingase futhi ibe nomthelela ovikelayo ezicutshini zobuchopho, iqhubeke yandise amandla ayo etiyetha okusiza ukwehlisa izimpawu zokuphazamiseka okuthile kobuchopho.
[Umsebenzi] Isetshenziswa kwezinye izindlela zokwelapha, i-huperzine A itholakale isebenza njenge-cholinesterase inhibitor, uhlobo lomuthi olusetshenziselwa ukuvimbela ukuwohloka kwe-acetylcholine (ikhemikhali ebalulekile ekufundeni nasekukhumbuleni).
Ayisetshenziswanga kuphela njengokwelashwa kwe-Alzheimer's, i-huperzine A kuthiwa ithuthukisa ukufunda nenkumbulo futhi ivikele ekunciphiseni kwengqondo okuhlobene neminyaka.
Ngaphezu kwalokho,huperzine Angezinye izikhathi isetshenziselwa ukuqinisa amandla, ukwandisa ukuphaphama, nokusiza ekwelapheni i-myasthenia gravis (isifo esizimele esithinta imisipha).
Isikhathi sokuthumela: Dec-04-2020