Huperzialuhlobo lobulembu obukhula eTshayina. Inxulumene nobulembu beeklabhu (usapho lweLycopodiaceae) kwaye yaziwa kwezinye iingcali ngezityalo njengeLycopodium serratum. I-moss yonke elungisiweyo yayisetyenziswe ngokwesiko. Amalungiselelo amayeza anamhlanje asebenzisa kuphela i-alkaloid ekwanti eyaziwa ngokuba yi-huperzine A. I-Huperzine A yi-alkaloid efumaneka kwi-huperzia eye yaxelwa ukunqanda ukuchithwa kwe-acetylcholine, into ebalulekileyo efunekayo yinkqubo ye-nervous yokuhambisa ulwazi kwiseli ukuya kwiseli. Uphando lwezilwanyana lucebise ukuba i-huperzine A'Ukukwazi ukugcina i-acetylcholine kunokuba nkulu kunokwamanye amayeza kagqirha. Ukulahleka komsebenzi we-acetylcholine luphawu oluphambili lweengxaki ezininzi zomsebenzi wobuchopho, kubandakanya i-Alzheimer'isifo . I-Huperzine A inokuba nefuthe elikhuselayo kwizicubu zobuchopho, inyuse ngakumbi amandla ayo okucinga ukunceda ukunciphisa iimpawu zokuphazamiseka kwengqondo.

Huperzine A

[Umsebenzi] Isetyenziswe kunyango olulolunye, i-huperzine A ifunyenwe isebenza njenge-cholinesterase inhibitor, uhlobo lweyeza elisetyenziselwa ukuthintela ukuchithwa kwe-acetylcholine (ikhemikhali ebalulekileyo yokufunda kunye nememori).

 

Ayisetyenziswanga kuphela njengonyango lwe-Alzheimer's isifo, i-huperzine A ikwatsho ukuba yonyusa ukufunda kunye nenkumbulo kunye nokukhusela ngokuchasene nokuncipha kwengqondo okunxulumene nobudala.

 

Ukwengeza,huperzine Angamanye amaxesha isetyenziselwa ukunyusa amandla, ukwandisa ukuphaphama, kunye nokunceda kunyango lwe-myasthenia gravis (i-autoimmune disorder echaphazela imisipha).

Huperzine A111


Ixesha lokuposa: Dec-04-2020