I-Procyanidins (OPC), igama lesayensi laseShayina, iwuhlobo lwama-bioflavonoid anesakhiwo samangqamuzana esikhethekile. Iyaziwa emhlabeni jikelele njenge-antioxidant yemvelo ephumelela kakhulu yokukhipha ama-radicals mahhala emzimbeni womuntu.
1. Ukukhipha ama-radical mahhala, i-antioxidant kanye nokulwa nokuguga
Ama-radicals wamahhala abhubhisa i-membrane yeseli, okuholela ekuguqukeni nasekuqhekekeni kwe-membrane yeseli, ukuze ingqamuzana lingakwazi ukumunca umsoco ovela ngaphandle, noma likhiphe udoti we-metabolic esitokisini, futhi lilahlekelwe ukumelana namabhaktheriya nama-virus. Ngemuva kokuqhekeka kwamangqamuzana, uketshezi lwamangqamuzana achithekile kanye nemfucumfucu kungena endaweni yeseli, okubangela ukusabela kwangaphandle njengokuvuvukala, ubuhlungu, ububomvu nokuvuvukala. Amaseli aya ngokwanda aqhekeka kanye ne-apoptosis, okuholela ekwehleni nasekuwohlokeni komsebenzi wesikhumba, imisipha, izitho zangaphakathi nezinye izicubu nezitho. Ama-radicals mahhala angenye yezinto ezibalulekile ezidala ukuguga komuntu kanye nezifo eziningi. Cishe i-80% ~ 90% yezifo zokuguga kanye nezifo eziwohlokayo zihlobene nama-radicals mahhala, okuhlanganisa ukufakwa kwamabala amnyama esikhumba, imibimbi, ukungezwani komzimba, ulwelwesi lwamehlo, umdlavuza, isifo senhliziyo nokunye. Isithasiselo sansuku zonke se-polyphenols yamagilebhisi singasusa ngempumelelo ama-radicals mahhala futhi sinikeze ukuvikelwa kwamahora angama-24 kumaseli ahlukahlukene abantu.
2. Fiphalisa amabala futhi wenze isikhumba sibe mhlophe
Kusukela esicini somzimba: ngokukhula kweminyaka kanye nokungcoliswa kwemvelo, umzimba womuntu ukhiqiza inqwaba yama-radicals mahhala, okuholela ekuphazamisekeni kwe-metabolic kanye nokukhiqizwa kwe-lipofuscin ngokweqile emzimbeni. Indlela yayo yokubola ivinjiwe, futhi inani elikhulu le-lipofuscin lifakwa enhliziyweni, isibindi, ubende, amaphaphu, izinso, ubuchopho namangqamuzana e-vascular, okwenza amabala e-lipofuscin, izitho ezilimazayo nemisebenzi ewohlokayo; I-Lipofuscin ifakwa kumangqamuzana esikhumba (ikakhulukazi isikhumba sobuso nesandla), enze amabala esikhumba, i-chloasma, amabala ovemvane namabala akhungathekile, athinta kakhulu ukubukeka kweziguli futhi abangele ubuhlungu obukhulu engqondweni ezigulini. I-Grape polyphenol proanthocyanidins yaziwa ngokuthi 'i-free radical scavenger enamandla kakhulu'. Ingabola i-lipofuscin, ivikele izitho ezihlukahlukene futhi inciphise amabala ombala emzimbeni. Ngaphezu kwalokho, ngokungafani nama-antioxidants ajwayelekile, ama-procyanidin angakwazi ukuwela umgoqo wegazi nobuchopho futhi avikele ubuchopho nemithambo yegazi kuma-radicals mahhala.
Kusuka esikhumbeni: umoya ongcolile, imisebe ye-ultraviolet enamandla kanye nekhompyutha, izimonyo (izinongo, izivimbelakuvunda, izingulube) nezinye izici ziyimbangela yokukhiqizwa kwama-radicals mahhala angaphandle, okwenza ingaphandle lamangqamuzana esikhumba ahlaselwe kakhulu. . Enqubweni yokuhlaselwa kwama-radical mahhala kanye nokucekelwa phansi kwamaseli, inani elikhulu lamaseli liyafa kanye nokuphazamiseka kwe-metabolic, futhi ukungcola kumaseli akukwazi ukuguqulwa, okuholela ekufakweni kwe-pigment, inani lamaseli amasha liyancipha kakhulu (amaseli amasha abalulekile. isici ekugcineni ubungqabavu besikhumba). I-proanthocyanidin yamagilebhisi ayikwazi nje ukususa ngempumelelo ama-radicals mahhala emzimbeni womuntu, kodwa futhi ikhuthaze umzimba wesikhumba, ihlukanise ukungcoliswa kwemvelo kanye nokulimala kwezimonyo, ukubola kwe-melanin futhi kufinyelele umphumela wesikhumba esimhlophe. I-Procyanidin OPC iyi-ejenti yemvelo evala ilanga, engavimbela imisebe ye-ultraviolet ukuthi ingalimazi isikhumba. Ukukhanya kwelanga kanye nemisebe ye-ultraviolet kungabulala u-50% wamaseli esikhumba somuntu, kodwa uma uthatha ama-polyphenol amagilebhisi ukuze uvikeleke, cishe u-85% wamaseli esikhumba angasinda ekufeni futhi ngempumelelo 'avikele elangeni'.
3. Gcina ukunwebeka kwesikhumba futhi unciphise imibimbi
I-dermis yesikhumba ingeyezicubu ezixhumeneyo. I-collagen ne-elastin eqinile equkethwe kuyo idlala indima ebalulekile kuso sonke isakhiwo sesikhumba. Amagilebhisi e-polyphenol proanthocyanidins adlala indima ekabili esikhumbeni: ngakolunye uhlangothi, angakhuthaza ukwakheka kokuxhumanisa okufanelekile kwe-collagen; Ngakolunye uhlangothi, njenge-free radical scavenger ephumelelayo, ingavimbela "i-over crosslinking" yesikhumba, ivimbele ukubukeka kwemibimbi yesikhumba nezibazi, futhi igcine isikhumba sithambile futhi sibushelelezi. Amagilebhisi e-polyphenol proanthocyanidins angaphinde avimbele ukukhiqizwa kwe-elastase eqinile, avimbele umsebenzi wayo, futhi avimbele ama-radicals mahhala noma i-elastase eqinile ekwehliseni amaprotheni aqinile, ukuze athuthukise ngaphakathi impilo yesikhumba, anciphise izifo zesikhumba nemibimbi, futhi aqede ngisho nezibazi.
4. I-PMS (i-premenstrual syndrome)
Wonke umuntu wesifazane ngeke angayazi i-PMS (i-premenstrual syndrome). Izimpawu ezivamile ze-PMS yilezi: ubuhlungu, ukuvuvuka kwebele, isisu esingalingani, ukuqunjelwa kobuso, ubuhlungu be-pelvic obungaqinisekile, ukuzuza isisindo, ukungasebenzi kahle kwemilenze, ukuntengantenga kwemizwelo, ukujabula, ukucasuka, ukucindezeleka kanye nekhanda elibuhlungu lemizwa. Lezi zimpawu zisukela ekuphenduleni okuvamile komzimba kuya ezingeni le-estrogen ne-progesterone emzimbeni