U-Huperzia, inzalelwane yobulembu e-China, unxulumana ngokusondeleyo ne-baseball club moss kwaye ukhankanywa ngokwesayensi njenge-Lycopodium serratum. Ngokwemveli, i-stallion moss yayisetyenziswa, kodwa ukulungiswa kweti yemifuno yanamhlanje ngoku kugxininise kwi-alkaloid huperzine A. Le alkaloid, efumaneka kwi-huperzia, ibonise isithembiso ekuthinteleni ukuthotywa kwe-acetylcholine, i-neurotransmitter ebalulekileyo kunxibelelwano lwe-intercellular kwi-nervous system. uphando malunga nezilwanyana bespeak ukuba i-huperzine A inokodlula iyeza elithile likagqirha kwi-degree ye-acetylcholine. kunikwe ukuba ilahleko yomsebenzi we-acetylcholine luphawu oluphambili lokuphazamiseka kwengqondo okunxulunyaniswayo njengesifo sika-Alzheimer, i-huperzine A's enokubakho kwiimpembelelo ze-neuroprotective iyifakela i-intrigue ukhetho lokuthomalalisa iimpawu ezinxulumene nezi meko.
Kwiyeza lokukhetha, i-huperzine A isebenza njenge-cholinesterase inhibitor, uhlobo lweyeza elithintela ukuchithwa kwe-acetylcholine, ebalulekileyo kwinkqubo yokuqonda njengokufunda kunye nenkumbulo. Ngaphandle kwesicelo sayo kunyango lwe-Alzheimer's, i-huperzine A ikholelwa ukuba iya kuphucula umsebenzi wokuqonda, ukunyanzeliswa kokunciphisa ingqondo ye-age-associate, ukunyusa iqondo lamandla, ukukhuthaza ukulinda, kunye nokuxhasa ulawulo lwe-myasthenia gravis gravis, ukuphazamiseka kwe-autoimmune kuchaphazela ukusebenza kwemisipha. Uluhlu oluhlukeneyo lwenzuzo enokubakho lunyanzeliswa kwi-huperzine A igxininisa ukuguquguquka kwayo kwidilesi enxulumene nezempilo enxulumene nokusebenza kwengqondo kunye namandla okuqonda.
ukuqondaiindaba zobuchwepheshezibandakanya ukuhlala unolwazi malunga nokukhuthazwa kuphando lwezenzululwazi kunye nokuveliswa kwezempilo. Kumxholo we-huperzine A, uphando oluqhubekayo lunokuthi luphande unyango olunokubakho ngakumbi, olunokuthi luveze isicelo esitsha sale khompawundi yendalo ekutsaleni ingxaki ye-neurological kunye nomonakalo wokuqonda. Njengoko icandelo leyeza lokukhetha liqhubeka nokuvela, i-huperzine A isiseko ngaphandle njengesithembiso sokukhuthaza impilo yengqondo kunye nokujongana nesidingo esinzima somntu oneemeko ezifana nesifo sika-Alzheimer kunye nokuncipha kwengqondo okunxulumene neminyaka. Kuyimfuneko ukuphuhlisa uphuhliso lwexesha elizayo ekusebenziseni i-huperzine A, njengoko ibamba isithembiso esibalulekileyo kubukumkani bempilo yengqondo kunye nempilo ye-neurological.
Ixesha lokuposa: Feb-25-2022