Isicatshulwa sembewu yomdiliyaioligomeric proanthocyanidins, i-bioflavonoid enesakhiwo esikhethekileyo semolekyuli, yamkelwa njengeyona antioxidant isebenzayo yendalo emhlabeni.Isicatshulwa sembewu yomdiliya ngumgubo obomvu omdaka obomvu, unomoya omncinci, u-astringent, unyibilika emanzini kunye nezinyibiliki ezininzi eziphilayo.Iimvavanyo zibonise ukuba umthamo we-antioxidant wembewu yomdiliya isicatshulwa i-oligomeric proanthocyanidins yayingamaxesha angama-50 e-vitamin E kunye namaxesha angama-20 e-vitamin C, kwaye izinga lokufunxa lalikhawuleza kwaye liphelele.Emva kwemizuzu engama-20, i-concentration ephezulu yegazi yafikelelwa, kwaye isiqingatha sobomi be-metabolism sasiyi-7 iiyure.

Kukholelwa ukuba kubomi banamhlanje abantu banikela ingqalelo ngakumbi nangakumbi kwimpilo, igama elithi “imbewu yomdiliya essence oligomeric proanthocyanidins” ayingomntu wasemzini kuthi.Namhlanje, uXiaobian uza kwazisa ukusebenza kwe-13 kwembewu yomdiliya ioligomeric proanthocyanidins ngokukodwa.

1. Uxinzelelo lwegazi oluphantsi kunye ne-cholesterol

Ngokukhula, i-elastic fibers kwi-arteries iya kuba nzima ngokuthe ngcembe, eyona nto ibangela umfutho wegazi ophezulu kubantu abadala.Imbewu yomdiliya isicatshulwa ioligomeric proanthocyanidins inokunyusa ukuqina kwemithambo yegazi kunye noxinzelelo lwegazi olusezantsi.Izigulana ezithatha imbewu yeediliya isicatshulwa oligomeric proanthocyanidins emva kwexesha elithile, uxinzelelo lwegazi luya kuncitshiswa kakhulu.Imbewu yomdiliya isicatshulwa ioligomeric proanthocyanidins inokunciphisa i-cholesterol embi, inciphise i-cholesterol embi efakwe kwiindonga zemithambo yegazi, kwaye inciphise uxinzelelo lwegazi ngokuthintela umsebenzi we-reverse transcriptase.

2. Thintela i-arteriosclerosis, isifo senhliziyo kunye ne-stroke

Isifo senhliziyo sibalelwa kwi-50% yokufa okupheleleyo eUnited States minyaka le.I-Arteriosclerosis yinto ebalulekileyo ebangela isifo senhliziyo.I-arteriosclerosis inokuthintela ukuhamba kwegazi, njenge-angina pectoris okanye i-myocardial infarction entliziyweni, ukulahlekelwa yinkumbulo okanye ukubetha kwengqondo.Iyeza lokunyanga esi sifo yimbewu yomdiliya isicatshulwa ioligomeric proanthocyanidins, esebenzayo kwaye ikhuselekile.Ayinakukhusela kuphela udonga lwangaphakathi lwemithambo yegazi emonakalweni, kodwa iphinde ithintele iiplatelet ekujikeni nasekwenzeni amahlwili egazi, ukuze kuncitshiswe umngcipheko wokubetha kwentliziyo.

3. Umhlaza

Iimpembelelo ezichasene nomhlaza wembewu yomdiliya zichazwe kwijenali yaseMelika iSayensi.Izifundo zexesha elide zibonise ukubaimbewu yomdiliya isicatshulwa oligomeric proanthocyanidinsinokunciphisa izinga lezehlo zomhlaza ezahlukeneyo ukuya kumlinganiselo ophezulu.Olunye uphononongo lubonise ukuba izinga lomhlaza labantu abanamazinga aphantsi evithamin E laliphindwe kali-11.4 elo labantu abaqhelekileyo.Nangona kunjalo, umsebenzi we-antioxidant wembewu yomdiliya isicatshulwa i-oligomeric proanthocyanidins ngamaxesha angama-50 kune-vitamin E. Imbewu yomdiliya isicatshulwa i-oligomeric proanthocyanidins inokukhusela iiseli ezibulala iiseli zomhlaza kunye nokwandisa ixesha lomsebenzi weeseli zomhlaza.

4. Nqanda isilonda

Izinga lokwenzeka kwesilonda esiswini liphezulu kakhulu kuluntu lwanamhlanje.Esona sizathu siphambili sesilonda esiswini kukukhawuleziswa kwesigqi sobomi babantu kunye nokwanda koxinzelelo lwengqondo.Ukuhlala kweli lizwe ixesha elide, ukukhuselwa kwe-histamine esiswini kwanda ngokufanelekileyo, okukhokelela kwisilonda sesisu.Imbewu yomdiliya isicatshulwa ioligomeric proanthocyanidins inciphisa i-histamine, ikhusela udonga lwesisu nge-gastric mucosa, inciphisa ukhukuliseko olungakumbi lwezilonda kudonga lwesisu, ishwabene indawo yesilonda kwaye inceda ukunyanga izilonda.Amanye amachiza ezilonda zesisu ikakhulu anyanga isilonda esiswini ngokuthintela ukukhuselwa kweasidi esiswini, nto leyo edla ngokukhokelela kwiimpendulo ezifana ne-dyspepsia.Imbewu yomdiliya isicatshulwa ioligomeric proanthocyanidins inokuthintela ngokufanelekileyo izilonda ezizenzekelayo okanye zesisu kunye ne-duodenal ebangelwa yi-aspirin, i-steroids kunye neziyobisi ze-NSSID.

5. Ukuphelisa intlungu ye-arthritis kunye nokuvuvukala

Kwangoko ngeminyaka yee-1950, umsebenzi wokuchasana nokudumba kweumdiliya bonad i-oligomeric proanthocyanidins iye yaqatshelwa.Inokuthintela ukuhlanganiswa kunye nokukhululwa kwezinto ezininzi ezivuthayo.Imbewu yomdiliya isicatshulwa i-oligomeric proanthocyanidins inokudityaniswa ngokukhethiweyo kwizicubu ezidibeneyo zamalungu ukukhusela ukudumba kwamalungu, ukunceda ukuphilisa izicubu ezonakeleyo kunye nokuthomalalisa iintlungu, ngoko ke imbewu yomdiliya isicatshulwa se-oligomeric proanthocyanidins sinefuthe elibalulekileyo kwiindidi ezahlukeneyo ze-arthritis.

6. Ukuphucula i-prostatitis

Ukudumba eneneni yinkqubo ye-pathological enokuthi yenzeke kuyo nayiphi na indawo yomzimba womntu.Yimpendulo yoxinzelelo kumonzakalo, usulelo kunye nokuvuselela.Ingabonakaliswa kwiimpawu ezahlukeneyo, ezifana nokubomvu, intlungu, umkhuhlane kunye nokungasebenzi.I-Prostatitis sisifo esiqhelekileyo kumadoda.Sisifo esivuthayo esibangelwa yi-prostate dysfunction phantsi kwesenzo se-prostaglandin PGE2.Imbewu yamagilebhisi isicatshulwa i-oligomeric proanthocyanidins inokuphucula iimpawu ze-prostatitis kunye nokuphucula umgangatho wobomi bezigulane ze-prostate ngokuvimbela ukukhululwa kwe-PGE2.

7. Nqanda ukwaliwa

I-antianaphylaxis yembewu yomdiliya isicatshulwa i-oligomeric proanthocyanidins inxulumene nesiphumo sayo se-antihistamine.Kukho iintlobo ezimbini zeeseli emzimbeni womntu ezibizwa ngokuba yi-basophils kunye neeseli zemast, eziqulethe izinto ezikhuthazayo.I-radicals yamahhala isebenza kwiimbumba zeeseli zezi zimbini zeeseli, ezikhokelela ekuqhekekeni kweeseli kunye nokukhululwa kwezinto ezikhuthazayo.Xa umzimba udibana nezinye izinto zangaphandle, ezifana ne-pollen, uthuli, iziyobisi, iiprotheni zomzimba zangaphandle (ezifana nentlanzi, i-shrimp kunye nezinye iintlanzi zaselwandle), iimpawu ze-allergies ziya kwenzeka.Ngokungafaniyo namanye asetyenziswa ngokuqhelekileyo amayeza okulwa nokwaliwa, imbewu yomdiliya isicatshulwa ioligomeric proanthocyanidins ayisebenzi nje kuphela, kodwa ayinazo iziphumo ebezingalindelekanga ezifana nokutyhafa, ukudakumba, njalo njalo, ezingayi kuchaphazela umsebenzi oqhelekileyo kunye nobomi.

8. Khusela ingqondo

Imbewu yomdiliya kuphela kwe-antioxidant enokubonelela ngokhuseleko kwiiseli zengqondo ngomqobo wegazi-ubuchopho.Ngoko ke, inokuthintela isifo sika-Alzheimer.Ukongeza, iyakwazi ukuzinzisa umqobo wegazi-ingqondo kwaye ithintele izinto ezinobungozi kunye netyhefu ukuba zingangeni engqondweni, ukuze zikhusele ingqondo.

9. Ukuthintela kunye nokunyangwa kwe-asthma kunye ne-emphysema

Imbewu yomdiliya isicatshulwa oligomeric proanthocyanidins iluncedo kwizigulana ezinesifuba kunye ne-emphysema.Isifuba somoya sibangelwa ikakhulu kukwaliwa kwibronchus.Imbewu yomdiliya isicatshulwa ioligomeric proanthocyanidins inokuthintela ukuveliswa kwehistamine kunye nezinye izinto ezichaseneyo, ngoko ke iyasebenza kakhulu ekuthinteleni nasekunyangeni isifuba.Imbewu yomdiliya isicatshulwa oligomeric proanthocyanidins ikwanciphisa iimpawu ezinxulumene ne-emphysema, ezifana nokukhohlela, ubuthathaka, umfinya kunye nosulelo lwendlela yokuphefumla.

10. Ukuthintelwa kwe-cataract kunye ne-glaucoma

Abalandeli bakamabonwakude kunye nabalandeli bekhompyuter abahleli phambi kwesikrini ixesha elide baya kuchaphazeleka kumonakalo onamandla kakhulu wemitha emehlweni abo, eyona nto ingumonakalo weradicals yasimahla kwilensi kunye neretina.EUnited States, malunga ne-40000 abantu abaziimfama ngenxa ye-cataract minyaka le.Imbewu yomdiliya isusa iiradicals zasimahla emzimbeni kwaye ikhusela i-oxidation yeeradicals zasimahla kwiiproteni zelensi, ukuze kuthintelwe ukwenzeka kwecataract.Imbewu yomdiliya isicatshulwa ioligomeric proanthocyanidins inokuphucula kakhulu ukuxhathisa kwemithambo, inciphise ukungena kwemithambo, ngaloo ndlela ithintele ukuvuza kwezinye izinto egazini, kwaye ithintele ukwenzeka kweretinitis yeswekile.

Iglaucoma ibangelwa luxinzelelo oluphezulu lwe-intraocular.Imbewu yomdiliya isicatshulwa i-oligomeric proanthocyanidins kulula ukuyibopha kunye ne-collagen, ukuze umonakalo omkhulu wamahhala kwi-collagen unokupheliswa ngembewu yomdiliya i-oligomeric proanthocyanidins ngaphambi kokuba ithintele i-glaucoma.Ngapha koko, imbewu yomdiliya ikhuphe i-oligomeric proanthocyanidins inokuphinda ilungise i-collagen eyonakaliswe ziiradicals zasimahla, ngoko ke imbewu yomdiliya isicatshulwa i-oligomeric proanthocyanidins ingasetyenziselwa ukunyanga iglaucoma.

11. Ukukhusela ngokufanelekileyo amazinyo kunye neentsini

I-caries yamazinyo ibangelwa yi-cariogenic bacteria emlonyeni.Le ntsholongwane inokubolisa iswekile ukuze ivelise iasidi, ukuze yenze umhlwa amazinyo, yenze imingxunya yeecaries, iveze imithambo-luvo yamazinyo engaphakathi, ize yenze abantu babe neentlungu ezinganyamezelekiyo.Nangona kunjalo, ibhaktheriya ye-cariogenic inokudlala indima yayo ye-cariogenic kuphela ngokufaka i-fibrin eyinkimbinkimbi kwisithsaba okanye kumphezulu wezinyo.Imbewu yomdiliya ikhupha ioligomeric proanthocyanidins inokubophelela kule protein fiber, ibathintele ekubopheni benze iplaque kwaye banamathele emazinyweni abo, ukuze ibhaktiriya yecariogenic ilahlekelwe "yindawo esisiseko".Phantsi kokuhlanjwa kwamathe emlonyeni, iintsholongwane azikwazi ukubambelela emazinyweni ixesha elide, ngoko azikwazi ukubolisa iswekile ukuze zivelise iasidi yokugrulisa amazinyo.

12. Ukunciphisa i-premenstrual tension syndrome

Iimpawu eziqhelekileyo ze-premenstrual tension syndrome zezi: intlungu yokuya exesheni, ukudumba kwebele, ukungonwabi kwesisu, ukudumba kobuso, iintlungu ze-pelvic ezingaqinisekanga, ukuzuza ubunzima, ukungasebenzi kakuhle kwe-endocrine, ukungazinzi ngokweemvakalelo, imincili, ukucaphuka, ukudandatheka kunye nentloko yemithambo-luvo.Imbewu yomdiliya isicatshulwa ioligomeric proanthocyanidins inokuphelisa ukuxinezeleka kokuya exesheni ngokusebenzisa iipropathi ezichasene nokwaliwa.

13. Ukuchasa ukuguga

Kumazwe aseYurophu naseMelika, imbewu yomdiliya essence oligomeric proanthocyanidins zaziwa ngokuba "ziivithamini zesikhumba" kunye "nezithambiso zomlomo".Zizimveliso zobuhle ezidumileyo kubafazi bayo yonke iminyaka.

Ulusu lutyebile kwizicubu ezixhamlayo, eziqukethe i-collagen kunye ne-elastin, edlala indima ebalulekileyo kwisakhiwo sonke solusu.Oku kunyaniseka kuxhomekeke kwinto ebizwa ngokuba yi "collagen cross-linking" - i-collagen yenza i-microfibrils, kwaye i-microfibrils ezimbini zixhunyiwe, njengeleli.I-crosslinking ephakathi iyimfuneko kuba kuphela ngale ndlela inokugcinwa ingqibelelo yesakhiwo solusu.Nangona kunjalo, i-oxidation ye-radical yamahhala inokubangela ukudibanisa okugqithisileyo, okwenza esi sakhiwo sibe lukhuni kwaye sibe brittle.Eluswini, oku kuphambana okugqithisileyo kubonakala njengemibimbi kunye ne-vesicles.

Imbewu yomdiliya isicatshulwa ioligomeric proanthocyanidins idlala indima emibini apha: kwelinye icala, inokukhuthaza ukwakheka kwe-cross-linking eyiyo ye-collagen.Kwelinye icala, njenge-scavenger esebenzayo yasimahla, inokuthintela ukwenzeka kwe-"crosslinking egqithisileyo".Ngaloo ndlela, ikhusela ukubonakala kwemibimbi yesikhumba kunye ne-vesicles kwaye igcina ulusu luthambile kwaye lugudile.

Yintoni eyenza i-elastic yesikhumba enye inxalenye yesikhumba - i-elastin enzima.I-elastin enzima inokuthotywa ngomonakalo omkhulu wamahhala okanye i-elastase.Ulusu olungenayo i-elastin eqinile lukhululekile kwaye lubuthathaka, okwenza abantu babonakale bebadala.I-radicals yamahhala ivimba ukuveliswa kwe-elastin enzima kwaye inqanda umsebenzi wayo.Imbewu yomdiliya ikhupha ioligomeric proanthocyanidin ikhupha iiradicals zasimahla kunye nokuphucula impilo yolusu ngaphakathi.Kungenxa yoko le nto imbewu yomdiliya i-oligomeric proanthocyanidins ibizwa ngokuba "ziivithamini zesikhumba" kunye "nezithambiso zomlomo".