Video shows what pycnogenol means. Any of a group of flavonoids extracted from the bark of pine trees, especially proanthocyanidins.. An antioxidant dietary supplement containing such an extract. pycnogenol synonyms: OPC, proanthocyanidin. Pycnogenol Meaning. How to pronounce, definition audio dictionary. How to say pycnogenol. Powered by MaryTTS, Wiktionary