Huperzia, oo u dhalatay dalka Shiinaha, waxa ay aad ugu xidhan tahay cawska naadiga baseball-ka waxana si cilmiyeysan loogu xusaa Lycopodium serratum. Dhaqan ahaan, moss stallion ah ayaa la isticmaali jiray, laakiin diyaarinta shaaha geedo yaryar oo casri ah ayaa hadda diiradda saaraya alkaloid huperzine A. Alkaloidkan, oo laga helo huperzia, ayaa muujiyay ballanqaad ka hortagga hoos u dhaca acetylcholine, neurotransmitter muhiim u ah isgaarsiinta intercellular ee habka dareenka. cilmi baaris ku saabsan xayawaanka ayaa sheegaya in huperzine A laga yaabo inay dhaafto daawooyinka loo qoro qaarkood ee sii wadida shahaadada acetylcholine. Marka la eego in luminta shaqada acetylcholine ay tahay sifo muhiim ah oo ka mid ah cilladaha maskaxda ee kala duwan sida cudurka Alzheimers, huperzine A's saamaynta neuroprotective ee suurtagalka ah waxay calaamad u tahay ikhtiyaarka xiisaha leh ee lagu nafiso calaamadaha calaamadaha xaaladahan.
Daawada ikhtiyaarka ah, huperzine A waxay u shaqeysaa sidii cholinesterase inhibitor, nooc daawo ah oo xannibaysa kala-baxa acetylcholine, oo muhiim u ah nidaamka garashada sida barashada iyo xusuusta. Marka laga soo tago codsigeeda daaweynta Alzheimers, huperzine A waxaa la rumeysan yahay in ay kor u qaaddo shaqada garashada, ka taxaddarka hoos u dhaca garashada ee da'da, kor u qaadida heerka tamarta, kor u qaadka feejignaanta, iyo taageeridda maaraynta myasthenia gravis gravis, xanuunka difaaca jirka ee saameeya shaqada muruqa. Baaxadda kala-duwan ee faa'iidada suurtagalka ah ayaa lagu tiriyaa huperzine A waxay hoosta ka xariiqday kala duwanaanshaheeda si ay wax uga qabato walaacyada caafimaad ee kala duwan ee la xidhiidha shaqada maskaxda iyo awoodaha garashada.
fahamkawararka tignoolajiyadaku lug lahaansho wargelin ku saabsan horumarinta cilmi-baarista sayniska iyo ikhtiraacida daryeelka caafimaadka. Marka la eego macnaha huperzine A, sahan socda waxay u badan tahay inay cilmi baaris dheeraad ah ku sameyso daweynteeda, taasoo suurtogal ah inay daaha ka qaaddo codsi cusub oo loogu talagalay xaruntan dabiiciga ah ee jiidaya cilladda neerfaha iyo dhaawaca garashada. Iyada oo qaybta dawada ikhtiyaarka ah ay sii socoto inay horumarto, huperzine A saldhigga u ah ololeeyaha ballan-qaadka ee kor loogu qaadayo caafimaadka garashada iyo wax ka qabashada baahida adag ee qofka qaba xaaladaha sida cudurka Alzheimers iyo hoos u dhaca garashada xidhiidhka da'da. Waa lagama maarmaan in la horumariyo mustaqbalka ee isticmaalka huperzine A, maadaama ay ku dhejinayso ballanqaad muhiim ah boqortooyada caafimaadka maskaxda iyo fayoobaanta neerfaha.
Waqtiga boostada: Feb-25-2022