Huperzine A
[Magaca Laatiinka]Huperzia serratum
[Isha] Huperziceae geedo dhan oo ka yimid Shiinaha
[Muuqaalka] Brown ilaa caddaan
[Wax ka kooban]Huperzine A
[Tilmaamin]Huperzine A1% - 5%, HPLC
[Solubility] Ku milmay chloroform, methanol, ethanol, wax yar oo biyo ku milmay
[Qaybta qaybta] 80 Mesh
[khasaaraha qallajinta] ≤5.0%
[Bir culus] ≤10PPM
[Hadhaaga sunta cayayaanka] EC396-2005, USP 34, EP 8.0, FDA
[Kaydinta] Ku kaydi meel qabow & qalalan, ka fogow iftiinka tooska ah iyo kulaylka.
[Nolosha shelf] 24 bilood
[ Xidhmada] Ka buuxaan durbaanno waraaqo ah iyo laba bac oo gudaha ah.
Waa maxay Huperzine A
Huperzia waa nooc ka mid ah moss oo ka baxa Shiinaha. Waxay la xiriirtaa mosses naadiyada (qoyska Lycopodiaceae) waxaana u yaqaan qaar ka mid ah botanists sida Lycopodium serratum. Moss-ka la diyaariyey oo dhan waxa loo isticmaali jiray dhaqan ahaan. Diyaargarowga dhirta casriga ah waxay isticmaalaan kaliya alkaloid-ka go'doonsan ee loo yaqaan huperzine A. Huperzine A waa alkaloid laga helo huperzia kaas oo la soo sheegay si looga hortago burburka acetylcholine, walax muhiim ah oo loo baahan yahay habdhiska dareenka si uu u gudbiyo macluumaadka unug ilaa unug. Cilmi-baadhista xayawaanku waxay soo jeedisay in awoodda huperzine A ee lagu ilaaliyo acetylcholine laga yaabo inay ka weyn tahay ta daawooyinka dhakhtar qoray qaarkood. Luminta shaqada acetylcholine waa astaanta aasaasiga ah ee dhowr cilladood oo shaqada maskaxda ah, oo uu ku jiro cudurka Alzheimers. Huperzine A waxa kale oo laga yaabaa in ay saameyn ka hortag ah ku yeelato unugyada maskaxda, iyada oo sii kordhinaysa awooddeeda aragtiyeed ee caawinta dhimista calaamadaha cilladaha maskaxda qaarkood.
[Shaqada] Loo isticmaalo dawo kale, huperzine A ayaa la ogaaday inay u dhaqanto sida cholinesterase inhibitor, nooc daawo ah oo loo isticmaalo si looga hortago burburka acetylcholine (kiimiko muhiim u ah barashada iyo xusuusta).
Kaliya maahan in loo isticmaalo daawaynta cudurka Alzheimers, huperzine A ayaa sidoo kale la sheegay inay kor u qaaddo waxbarashada iyo xusuusta iyo inay ka ilaaliso hoos u dhaca garaadka da'da.
Intaa waxaa dheer, huperzine A waxaa mararka qaarkood loo isticmaalaa si kor loogu qaado tamarta, kordhinta feejignaanta, iyo caawinta daaweynta myasthenia gravis (cudur difaaca jirka oo saameeya muruqyada).