[Latin Name] Stevia rebaudiana

[Plant Source]from China

[Specifications] 1.Stevia Extract Powder (Steviosides)

Total Steviol Glycosides 80%, 90%, 95%

2. Rebaudioside-A

Rebaudioside-A 40%, 60%, 80%, 90%, 95%, 98%

3. Stevioside 90%

One monomer in Steviol Glycosides

[Appearance] Fine white powder

Plant Part Used:Leaf

[Particle size] 80 Mesh

[Loss on drying] ≤5.0%

[Heavy Metal] ≤10PPM

[Shelf life] 24 Months

[Package] Packed in paper-drums and two plastic-bags inside.

[Net weight] 25kgs/drum

Stevia Extract

[Characteristics]

Stevia sugar features high sweetness and low calorie and its sweetness is 200 350  times of that  of cane sugar but its calorie is only 1/300 of that of cane sugar.

The component of stevia extract that gives it its sweetness is a mixture of various steviol glycosides. The components of sweetness in stevia leaves are stevioside, rebaudioside A, C, D, E and dulcoside A. Rebaudioside C, D, E and dulcoside A are small in quantity. The principal components are stevioside and rebaudioside A.

The quality of stevioside and rebaudiosideA is better than those of other components, which are commercially extracted and used in various applications.

The steviol glycosides present in stevia extract are referred to as “steviosides” or ¡°stevia extract¡±. Among these “steviosides”, the most common is Stevioside followed by RebaudiosideA. The Stevioside has a slight and pleasant herbal taste and the Rebaudioside-A has no herbal taste.

Although Rebaudioside C and dulcoside A are small in quantity in stevia extract, they are the major components giving bitter aftertaste.

[Function]

A large number of pharmaceutical tests have proved that stevia sugar has no side effects, carcinogens, and is safe for eating.

Compared with cane sugar, it can save 70% of the cost. With pure white color, pleasing taste and no peculiar smell, Stevia sugar is a new sugar source with broad perspective for development. Stevia rebaudianum sugar is the natural low hotsweet agent mostly similar to the flavor of cane sugar, approved to be used by State Ministry of Health and Ministry of Light Industry.

It is the third natural succedaneum of cane sugar and beet sugar with development and health care value, extracted from the leaves of the herbal vegetable of the composite family-stevia rebaudianum.

Heres the list people….
Methadone-oral 80-90%, halflife- 24-36 hours, rectal 76%
Ketobemiodone oral was 34% +/-10%, rectally 44% +/- 9%, half-life is 2.25- 2.45 hours
Meperidine rectal bioavailability is approximately 55%, 80% to 85% IM, elimination half-life 3.0 h
Buprenorphine highly protein bound 96%, sublingual bioavailability is approximately 30%, oral is 15-22%, 90-100% IM, elimination half-life is 12-44 hours
Hydromorphone– 5-8 times as potent as morphine, intranasal- 52.4%, Rectal administration 33% ,Oral-30-35%, (also reported as 50.7% +/- 29.8% oral; 33% +/- 22% rectal; 54.4% – 59.8% nasal)
Dihydrocodeine oral-20-21% halflife 4 hours
Heroin oral ~35% IV- 100% IM-85% Smoked (or vaporized?) 52-55% vaporized Semisynthetic derivative, Intranasal 44-61%
Fentanyl- Bioavailability 92% (transdermal), 50% (sublingual/ buccal (against cheek), Protein binding 80-85%, half-life 3-12 hours
Sufentanil intranasal bio- 78%,
Remifentanil Protein binding 70% (bound to plasma proteins) Half life 1-20 minutes
Alfentanil- IV ~100%, 92% protein binding, half life is 1.5-2 hours
Morphine ~32% oral/rectal, insuffulated- 15-20%, Chitosan(a linear polysaccharide that helps absorb drugs better) has been shown to increase nasal bioavailability of morphine from around 10-20% to over 60%, SC-60%, protein binding 30-40%, half-life is 2-3 hours
Oxycodone-oral 60-87% intranasal- widely varies 45-70%
Hydrocodone- oral bioavailability is not really known but it is around oxycodone bioavailability, ~70% of it is usually absorbed, half-life is 4-8 hours
Oxymorphone nasal bioavailabilty [43%] orals low 10-20%
Butorphanol -oral 5-17% due to high first pass metabolism
Tramadol- the absolute bioavailability of rectally admistered tramadol in the suppositories was 77.0%, Oral-68-72% (Increases with repeated dosing) Half life 5-7 hours
Codeine- following rectal or oral administration with a systemic availability of about 90%; in one study clearance varied 4-fold and systemic availability after oral dosage was between 50 and 84%
Diphenoxylate Protein binding 74-95% Half life 12-14 hours used for diarrhea, (does not appreciably cross the blood-brain barrier)
Pethidine(meperidine) Absorption Oral bioavailability is 50-60% in patients with normal hepatic function. IM 80-85%, Protein Binding 65-75%, Half Life 3-5 hours
Normeperidine is about half as potent as meperidine, but it has twice the CNS stimulation effects.
Pentazocine- Bioavailability ~20% orally, Half-life 2 to 3 hours

Opiate Antagonists
Naloxone oral- 2-4% (90% absorption but high first-pass metabolism), Half life 1-1.5 hours
Naltrexone Oral Bioavailability 5-40%, Protein binding 21%, Half life-4 hours (naltrexone),
and 13 hours (6-β-naltrexol) (metabolite)

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