[Latin Name] Griffonia simplicifolia

[Plant Source] Griffonia Seed

[Specifications] 98%; 99% HPLC

[Appearance] White fine powder

Plant Part Used: Seed

[Particle size] 80 Mesh

[Loss on drying] ≤5.0%

[Heavy Metal] ≤10PPM

[Pesticide residue] EC396-2005, USP 34, EP 8.0, FDA

[Storage] Store in cool & dry area, keep away from the direct light and heat.

[Shelf life] 24 Months

[Package] Packed in paper-drums and two plastic-bags inside.

[Net weight] 25kgs/drum

[What is 5-HTP]

5-HTP (5-Hydroxytryptophan) is a chemical by-product of the protein building block L-tryptophan. It is also produced commercially from the seeds of an African plant known as Griffonia simplicifolia 5-HTP is used for sleep disorders such as insomnia, depression, anxiety, migraine and tension-type headaches, fibromyalgia, obesity, premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), attention deficit-hyperactivity disorder (ADHD), seizure disorder, and Parkinson’s disease.

 [How does it work?]

5-HTP works in the brain and central nervous system by increasing the production of the chemical serotonin. Serotonin can affect sleep, appetite, temperature, sexual behavior, and pain sensation. Since 5-HTP increases the synthesis of serotonin, it is used for several diseases where serotonin is believed to play an important role including depression, insomnia, obesity, and many other conditions.

[Function]

Depression. Some clinical research shows that taking 5-HTP by mouth improve symptoms of depression in some people. Some clinical research shows that taking 5-HTP by mouth might be as beneficial as certain prescription antidepressant drugs for improving depression symptoms. In most studies, 150-800 mg daily of 5-HTP was taken. In some cases, higher doses have been used.

Down syndrome. Some research shows that giving 5-HTP to infants with Down syndrome might improve muscle and activity. Other research shows that it does not improve muscle or development when taken from infancy until 3-4 years of age. Research also shows that taking 5-HTP along with conventional prescription drugs does improve development, social skills, or language skills.

Anxiety 5-HTP was found to be protective against carbon dioxide-induced panic attacks. One study compared 5-HTP and the prescription medication clomipramine for anxiety. Clomipramine is a tricyclic antidepressant used for treating obsessive-compulsive disorder. 5-HTP was found to be somewhat effective in reducing anxiety symptoms, but not as effective as clomipramine.

Sleep 5-HTP supplements fared a little better for insomnia.5-HTP decreased the time required to get to sleep and decreased the number of nighttime awakenings. Taking 5-HTP along with GABA (gamma-aminobutyric acid), a relaxing neurotransmitter, reduced the time it took to fall asleep and increased the duration and quality of sleep. One study found that children with night terrors benefited from 5-HTP.

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BENEFITS OF MUSCADINE GRAPE SEED – LiveStrong.com

1) Anti-Cancer 2) Cardiovascular 3) Antioxcidant 4)Preservative

1) Anti-Cancer
Four varieties of muscadine grapes showed significant anti-cancer properties in a study conducted by the Department of Biological Sciences at Clemson University, South Carolina. In the test-tube study, scientists tested grape pomace, the solids left over after juice is extracted for wine production against a known carcinogenic substance.

Antioxidant activity and inhibition of tissue degrading enzymes were evaluated and found to be high in all four samples. However, two samples showed poor ability to protect against cellular mutations when exposed to another mutation-causing molecule.

Researchers concluded there was a good potential for the use of muscadine grape extract at preventing cancer.

2) Cardiovascular
Researchers at the Wake Forest University School of Medicine, Winston Salem, North Carolina, found that polyphenol antioxidants in muscadine grape seeds had a relaxing and dilating effect on arteries.

In the study, participants with coronary artery disease took 1,300 mg per day of muscadine grape seed extract for four weeks. There was no evidence of improved blood flow, reduced inflammation or increased antioxidant activity. However, diameter of certain arteries increased, implying potential blood pressure-lowering effects.

Researchers called for further research to determine whether these results indicate important health benefits of muscadine grape seeds. The study was published in the October 2010 issue of the “Journal of the American College of Nutrition.”

3) Antioxidant
In a study published in the April 2010 issue of the “Journal of Agricultural and Food Chemistry,” muscadine grape seeds showed the highest antioxidant levels in the grape, followed by the skin and pulp.

The seeds contained 87 percent phenolic antioxidant compounds, skins contained 11.3 percent and pulp contained 1.6 percent. The researchers identified a total of 88 different antioxidant compounds in muscadine grapes, 43 of which occurred in the seeds. Seventeen of the compounds were unique to muscadine grapes.

The study was conducted by the Department of Food Science and Human Nutrition, University of Florida, Gainesville.

4) Preservative
Muscadine grape seed extract may offer antibacterial and food preservative benefits, according to researchers at the Department of Food Science, Nutrition and Health Promotion at Mississippi State University.

In the study, two varieties of muscadines, one purple and one bronze-colored, were tested against three strains of E. coli bacteria, which is associated with food-borne intestinal illnesses.

The purple variety showed higher acidity and higher antioxidant levels than the bronze variety, though heating the seed extracts from the bronze grapes increased activity of one antioxidant compound by 83 percent.

Researchers concluded good potential for the use of muscadine grape seed extract as a preservative for juices and other beverages. The study was published in the July 2008 issue of the “Journal of Food Protection.”

Read more: https://www.livestrong.com/article/456898-muscadine-grape-seed-benefits/#ixzz2KWgliOfS