[Latin Name] Andrographis paniculata(Burm.f.)Nees

[Plant Source] Whole herb

[Specification] Andrographolides 10%-98% HPLC

[Appearance] White powder

Plant Part Used: Herb

[Particle size] 80Mesh

[Loss on drying] ≤5.0%

[Heavy Metal] ≤10PPM

[Storage] Store in cool & dry area, keep away from the direct light and heat.

[Shelf life] 24 Months

[Package] Packed in paper-drums and two plastic-bags inside.

[Net weight] 25kgs/drum

[What is Andrographis?]

Andrographis paniculata is a bitter tasting annual plant, referred to as the “King of Bitters.” It has white-purple flowers and it is native to Asia and India where it has been valued for centuries for its numerous medicinal benefits. Over the past decade, andrographis has become popular in America where it is often used alone and in combination with other herbs for a variety of health purposes.

[How does it work?]

According to Memorial Sloan-Kettering Cancer Center, the active ingredient in andrographis is andrographolides. Due to the andrographolides, andrographis has potent anti-inflammatory and antimalarial properties. It also has antimicrobial properties, meaning it can help to fight off and prevent infections from harmful microorganisms such as viruses, bacteria and fungi. In addition, andrographis is a powerful antioxidant and it can help to prevent free radical induced damage to your cells and DNA

[Function]

Cold and Flu

Scientists have discovered that andrographis helps to boost the immune system by stimulating the body’s production of antibodies and macrophages, which are large white blood cells that scavenge harmful microorganisms. It is taken for both the prevention and treatment of the common cold, and it is often referred to as Indian echinacea. It might help lessen the severity of cold symptoms such as sleeplessness, fever, nasal drainage and sore throat.

Cancer, Viral Infections and Heart Health

Andrographis may also help to prevent and treat cancer, and preliminary studies done in test tubes found that extracts of andrographis help to treat stomach, skin, prostate and breast cancer. Due to the herb’s antiviral properties, andrographis is used to treat herpes and it is also currently being studied as a treatment for Aids and HIV as well. Andrographis also promotes heart health and can help to prevent the formation of blood clots as well as to dissolve already formed blood clots. In addition, the herb relaxes smooth muscles in the walls of blood vessels and thereby helps to reduce high blood pressure.

Additional Benefits

Andrographis is used to promote gallbladder and digestive health. It also helps to support and strengthen the liver and it is used in combination with other herbs in several Ayurvedic formulations to treat liver disorders. Finally, andrographis extracts taken orally have been found to help neutralize the poisonous effects of snake venom.

Dosage and Precautions

The therapeutic dose of andrographis is 400 mg, twice daily, for up to 10 days. Although andrographis is considered safe in humans, the NYU Langone Medical Center warns that animal studies suggest that it may impair fertility. Andrographis may cause unwanted side effects such as headaches, fatigue, allergic reactions, nausea, diarrhea, altered taste and pain in the lymph nodes. It may also interact with certain medications and as with any supplement you should consult your health care practitioner before taking the herb.

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Effects of inbreeding and herbivory over generations in Horsenettle (Solanum carolinense L). Co-authors: Sarah Scanlon, Mark Mescher, Consuelo Demoraes and Andrew G. Stephenson

The effects of inbreeding depression are reported to be stronger in species that typically outcross than in species that typically self (Johnston and Schoen, 1996); moreover, the effects of inbreeding can vary among families within populations (Dudash et al., 1997). However, there is little information regarding the long-term effects of inbreeding depression in wild plant populations across multiple generations under natural conditions. This study investigated differences between inbred and outbred progeny from 8 maternal families of Horsenettle (Solanum carolinense L) in fitness, susceptibility to herbivory, and production of new sprouts. Sixteen plants—one inbred and one outbred progeny from each family—all carrying a different combination of self incompatibility alleles (Variants of the Polymorphic S locus) were planted in each of 2 fields in 2008, and data on fruit number, seeds per fruit, and overall fitness was collected. After the first growing season, plants overwintered and new sprouts emerged in early summer 2009. Data on time of sprouting, number of sprouts, leaf damage, and number of fruits, seeds/fruit and overall fitness was collected for the second generation. To examine how herbivory differentially affected the fitness of inbred and outbred progenies, one of the fields was sprayed with the contact insecticide Carbaryl 0.05% four times during the growing season. Genomic DNA was extracted and amplified from leaf samples of the new sprouts and self incompatibility alleles were identified to determine parentage. We found that (1) outbreds (both parents and second generation sprouts) produced significantly higher number of fruits and seeds, and had better fitness than inbreds, (2) outbred parents produced significantly higher numbers of new sprouts in the second generation and their sprouts germinated at least 2-3 days earlier, (3) both inbreds and outbreds from the sprayed field produced higher number of fruits and seeds, but (4) herbivory had a greater impact on the fruit production and fitness of outbred progeny.