[Latin Name] Epimedium sagittatnm Maxim

[Plant Source] Leaf

[Specification] Icariin 10% 20% 40% 50%

[Appearance] Light yellow fine powder

Plant Part Used: Leaf

[Particle size]80Mesh

[Loss on drying] ≤5.0%

[Heavy Metal] ≤10PPM

[Pesticide residue] EC396-2005, USP 34, EP 8.0, FDA

[Storage] Store in cool & dry area, keep away from the direct light and heat.

[Shelf life] 24 Months

[Package] Packed in paper-drums and two plastic-bags inside.

[Net weight] 25kgs/drum

[What is Epimedium?]

Epimedium extract is a popular aphrodisiac supplement and herbal sexual performance enhancer.It has a long history of traditional use in China for the alleviation of erectile dysfunction and for improving libido and fertility.

Also known as Horny Goat Weed, this supplement supposedly got its name after a farmer noticed that his flock of goats were particularly aroused after eating flowers of a specific type. These Epimedium flowers contain icariin, which is a natural compound that increases blood flow to sexual organs and promotes sex drive. Icariin has been found to increase Nitric Oxide synthesis as well as inhibiting the activity of the PDE-5 enzyme

[Icariin in Epimedium Extract]

Epimedium extracts powder contain an active phytochemical called icariin.Icariin has been observed to exhibit a number of useful traits, including renoprotective (liver protecting) hepatoprotective (kidney protecting), cardioprotective (heart protecting) and neuroprotective (brain protecting) effects.

It is also an antioxidant and can cause vasodilation. It exhibits antimicrobial characteristics and is thought to act as an aphrodisiac.

Icariin is classified as a flavonol glycoside, which is a type of flavonoid. Specifically, icariin is the 8-prenyl derivation of kaempferol 3,7-O-diglucoside, a prevalent and important flavonoid.

[Function]

1. Combat mental and physical fatigue;

2. Induce vasodilation and improve circulation;

3. Lower blood pressure in hypertensive patients;

4. Improve symptoms of erectile dysfunction (ED) through its action as a PDE5  inhibitor;

5. Improve the use of free testosterone in the blood;

6. Increase libido;

7. Alleviate symptoms of depression and stimulate improved cognitive function;

8. Protect against neurological degeneration.

Probing protein interactions in living mammalian cells on a microtubule bench. Mirela Boca et al (2015), Scientific Reports https://dx.doi.org/10.1038/srep17304

Microtubules are μm-long cylinders of about 25 nm in diameter which are present in the cytoplasm of eukaryotic cells. Here, we have developed a new method which uses these cylindrical structures as platforms to detect protein interactions in cells. The principle is simple: a protein of interest used as bait is brought to microtubules by fusing it to Tau, a microtubule-associated protein. The presence of a protein prey on microtubules then reveals an interaction between bait and prey. This method requires only a conventional optical microscope and straightforward fluorescence image analysis for detection and quantification of protein interactions. To test the reliability of this detection scheme, we used it to probe the interactions among three mRNA-binding proteins in both fixed and living cells and compared the results to those obtained by pull-down assays. We also tested whether the molecular interactions of Cx43, a membrane protein, can be investigated with this system. Altogether, the results indicate that microtubules can be used as platforms to detect protein interactions in mammalian cells, which should provide a basis for investigating pathogenic protein interactions involved in human diseases.

Griti is a learning community for students by students. We build thousands of video walkthroughs for your college courses taught by student experts who got an A+.

SUBSCRIBE to the channel and explore overviews for every concept in your calculus, chemistry and physics courses for FREE!

Register at www.GRITI.co
REQUEST VIDEOS FOR MORE HELP?
+ get thousands of study problems for exam prep