Huperziandi mtundu wa moss womwe umamera ku China. Zimagwirizana ndi mosses zamakalabu (banja la Lycopodiaceae) ndipo akatswiri ena amadzimadzi amadziwika kuti Lycopodium serratum. Moss yonse yokonzedwa idagwiritsidwa ntchito mwamwambo. Kukonzekera kwa zitsamba zamakono kumagwiritsa ntchito alkaloid yokhayokha yomwe imadziwika kuti huperzine A. Huperzine A ndi alkaloid yomwe imapezeka mu huperzia yomwe yanenedwa kuti imalepheretsa kuwonongeka kwa acetylcholine, chinthu chofunikira kwambiri chomwe chimafunika ndi dongosolo lamanjenje kuti lipereke chidziwitso kuchokera ku selo kupita ku selo. Kafukufuku wa zinyama wasonyeza kuti huperzine A'Kutha kusunga acetylcholine kungakhale kokulirapo kuposa kwamankhwala ena omwe amaperekedwa ndi dokotala. Kutayika kwa ntchito ya acetylcholine ndi gawo loyamba la zovuta zingapo zaubongo, kuphatikiza Alzheimer's's matenda. Huperzine A itha kukhalanso ndi chitetezo paminyewa yaubongo, ndikuwonjezera kuthekera kwake kothandizira kuchepetsa zizindikiro za zovuta zina zaubongo.

Huperzine A

[Ntchito] Yogwiritsidwa ntchito m'mankhwala osagwiritsidwa ntchito masiku onse, huperzine A yapezedwa kuti imakhala ngati cholinesterase inhibitor, mtundu wa mankhwala omwe amagwiritsidwa ntchito poletsa kusweka kwa acetylcholine (mankhwala ofunikira pophunzira ndi kukumbukira).

 

Osagwiritsidwa ntchito ngati chithandizo cha Alzheimer's's, huperzine A imanenedwanso kuti imathandizira kuphunzira ndi kukumbukira komanso kuteteza ku kuchepa kwa chidziwitso chokhudzana ndi ukalamba.

 

Kuphatikiza apo,huperzine ANthawi zina amagwiritsidwa ntchito kulimbikitsa mphamvu, kuonjezera tcheru, ndi kuthandizira kuchiza myasthenia gravis (matenda a autoimmune omwe amakhudza minofu).

Huperzine A111


Nthawi yotumiza: Dec-04-2020