Huperzia, mbadwa yaku China, amalumikizana kwambiri ndi baseball club moss ndipo amatchulidwa mwasayansi kuti Lycopodium serratum. Mwachizoloŵezi, ma stallion moss ankagwiritsidwa ntchito, koma kukonzekera kwa tiyi wamakono tsopano kumayang'ana pa alkaloid huperzine A. Alkaloid iyi, yomwe imapezeka mu huperzia, ili ndi lonjezano poletsa kuwonongeka kwa acetylcholine, neurotransmitter yofunikira kwambiri yolumikizana ndi ma neurotransmitter mu dongosolo lamanjenje. Kafukufuku wokhudza nyama anena kuti huperzine A ikhoza kupitilira mankhwala enaake omwe amaperekedwa ndi dokotala pakupitilira digiri ya acetylcholine. Poganizira kuti kutayika kwa ntchito ya acetylcholine ndi gawo lalikulu la matenda osiyanasiyana a muubongo monga matenda a Alzheimer's, Huperzine A's kuthekera kwa neuroprotective zotsatira amawonetsa kuti ndi njira yachidwi yochepetsera zizindikiro zokhudzana ndi izi.
Muzochita zamankhwala, huperzine A amagwira ntchito ngati cholinesterase inhibitor, mtundu wamankhwala womwe umalepheretsa kusuntha kwa acetylcholine, yofunika kwambiri pakuzindikira monga kuphunzira ndi kukumbukira. Kupitilira muyeso wake pamankhwala a Alzheimer's, huperzine A imakhulupirira kuti imathandizira kuzindikira magwiridwe antchito, kusamala motsutsana ndi kuchepa kwa chidziwitso chokhudzana ndi zaka, kulimbikitsa digiri ya mphamvu, kulimbikitsa kukhala maso, ndikuthandizira kasamalidwe ka myasthenia gravis gravis, vuto la autoimmune lomwe limakhudza kugwira ntchito kwa minofu. Kukula kosiyanasiyana kwa phindu lomwe lingakhalepo chifukwa cha huperzine A imatsimikizira kusinthasintha kwake pokhudzana ndi zovuta zokhudzana ndi thanzi zomwe zimakhudzana ndi ntchito yaubongo ndi luso la kuzindikira.
kumvetsankhani zamakonokuphatikizira kukhala odziwa zambiri za kukwezedwa mu kafukufuku wasayansi ndi kupangidwa kwachipatala. Pankhani ya huperzine A, kafukufuku wopitilira akuyenera kufufuza momwe angathandizire, ndikuwulula momwe angagwiritsire ntchito mankhwalawa pochotsa vuto la minyewa komanso kuwonongeka kwa chidziwitso. Pamene gawo lamankhwala osankha likupitilirabe kusinthika, huperzine A idakhazikitsidwa ngati wolimbikitsa kulimbikitsa thanzi lachidziwitso ndikuthana ndi zosowa zovuta za anthu omwe ali ndi matenda monga Alzheimer's komanso kuchepa kwa chidziwitso chokhudzana ndi zaka. Ndikofunikira kupititsa patsogolo chitukuko chamtsogolo pakugwiritsa ntchito huperzine A, chifukwa imagwirizana ndi lonjezo lofunikira muufumu wa thanzi laubongo ndi thanzi la mitsempha.
Nthawi yotumiza: Feb-25-2022