[Dzina lachilatini]Huperzia serratum

[Source] Huperziceae therere lonse laku China

[Maonekedwe]Wofiirira mpaka woyera

[Zopangira]Huperzine A

[Matchulidwe]Huperzine A 1% - 5%, HPLC

[Kusungunuka] Kusungunuka mu chloroform, methanol, ethanol, kusungunuka pang'ono m'madzi

[Kukula kwa kachigawo] 80 Mesh

[Kutaya pakuyanika] ≤5.0%

[Chitsulo Cholemera] ≤10PPM

[Zotsalira za mankhwala] EC396-2005, USP 34, EP 8.0, FDA

[Kusungirako] Sungani pamalo ozizira komanso owuma, khalani kutali ndi kuwala kwachindunji ndi kutentha.

[Moyo wa alumali] Miyezi 24

[Phukusi] Odzaza ndi mapepala-ng'oma ndi matumba awiri apulasitiki mkati.

[Huperzine A ndi chiyani]

Huperzia ndi mtundu wa moss womwe umamera ku China. Zimagwirizana ndi mosses zamakalabu (banja la Lycopodiaceae) ndipo akatswiri ena amadzimadzi amadziwika kuti Lycopodium serratum. Moss yonse yokonzedwa idagwiritsidwa ntchito mwachikhalidwe. Kukonzekera kwa zitsamba zamakono kumagwiritsa ntchito alkaloid yokhayokha yomwe imadziwika kuti huperzine A. Huperzine A ndi alkaloid yomwe imapezeka mu huperzia yomwe yanenedwa kuti imalepheretsa kuwonongeka kwa acetylcholine, chinthu chofunikira kwambiri chomwe chimafunika ndi dongosolo lamanjenje kuti lipereke chidziwitso kuchokera ku selo kupita ku selo. Kafukufuku wa zinyama wasonyeza kuti mphamvu ya huperzine A yosunga acetylcholine ingakhale yaikulu kuposa ya mankhwala ena olembedwa ndi dokotala. Kutayika kwa ntchito ya acetylcholine ndi gawo loyamba la zovuta zingapo za ubongo, kuphatikizapo matenda a Alzheimer's. Huperzine A itha kukhalanso ndi chitetezo paminyewa yaubongo, ndikuwonjezera kuthekera kwake kothandizira kuchepetsa zizindikiro za zovuta zina zaubongo.

[Ntchito] Yogwiritsidwa ntchito m'mankhwala osagwiritsidwa ntchito masiku onse, huperzine A yapezedwa kuti imakhala ngati cholinesterase inhibitor, mtundu wa mankhwala omwe amagwiritsidwa ntchito poletsa kusweka kwa acetylcholine (mankhwala ofunikira pophunzira ndi kukumbukira).

Osagwiritsidwa ntchito ngati chithandizo cha matenda a Alzheimer's, huperzine A imanenedwanso kuti imathandizira kuphunzira ndi kukumbukira komanso kuteteza ku kuchepa kwa chidziwitso chokhudzana ndi ukalamba.

Kuonjezera apo, huperzine A nthawi zina amagwiritsidwa ntchito kulimbikitsa mphamvu, kuonjezera tcheru, ndi kuthandizira kuchiza myasthenia gravis (matenda a autoimmune omwe amakhudza minofu).

Amazon-ES: https://kinix.us/zoro/2/es/B00JZ3XGXQ/info
Cranbiotix imapereka mabakiteriya 'ochezeka' a probiotic ndi ma cranberry extract.
Awa amapikisana pa malo ndi mabakiteriya 'oyipa'.
Proanthocyanidin, yomwe ili ndi ma proanthocyanidins, imathandizira thanzi la mkodzo.

(Onani https://nanohour.beckman.illinois.edu/Nanohour/Nanohour.html)

"Vuto la Dzino: Biomodification of Dentin Matrices monga Novel Strategy for Dental Therapies"

Prof. Ana Bedran-Russo (UIC College of Dentistry)

“Akuyerekezeredwa kuti mu United States, 350 miliyoni kukonzanso mano
(zodzaza) zimayikidwa chaka chilichonse m'maofesi a mano. Makumi asanu ndi limodzi pa zana a kubwezeretsedwako
m'malo mwa mankhwala obwezeretsa omwe alipo omwe alephera. Chifukwa chachikulu chakulephera kwa
kubwezeretsedwa kwa mano ndi caries yachiwiri (kuwola), kusonyeza kuwonjezeka kwa permeability
ndi debonding pakati dzino ndi restorative biomaterial. Zomatira zamano zamakono
machitidwe obwezeretsa amadalira kusungidwa kwa micromechanical zobwezeretsa ndi
kulowetsedwa kwa utomoni wa hydrophilic ndi hydrophobic mu malo olemera a collagen
dentini. Laborator yathu ku UIC yakhazikika pakumvetsetsa dzino
biochemistry / biomechanics ndikuwunika njira zama biomimetic zaukadaulo
mankhwala obwezeretsa/otsitsimutsa. Makamaka kuyanjana kwa olygomeric
proanthocyanidins agents (OPC) okhala ndi matrices a dentini kuti apititse patsogolo makina
katundu ndi kuchepetsa biodegradation mitengo. Chidziwitso ichi chidzapereka (1)
mwachidule za zovuta m'malo ovuta amkamwa (2) zoperewera zapano
mankhwala a mano ndi (3) njira zolumikizirana za OPC ndi mtundu wa I collagen,
proteoglycans ndi matrix metalloproteinases (MMPs).