A song about Macromolecules (a.k.a. Biomolecules, Carbon-Based Molecules, or the molecules of life) and Nutrition (Carbohydrates, Lipids, Proteins, and Nucleic Acids), based on PSY’s “Gangnam Style.”

Lyrics written by and song sung by a simple high school science teacher named Mr. Hsu.

Special thanks to Mr. Moore, Mrs. O’Brien, Mr. Kelly, Mrs. Wiemer, Mr. Walker, Mrs. Bourisseau, and Mrs. Brem for helping out by dancing and being filmed!

mp3 available:

Captions are available so you know what is actually being taught and sung (feel free to turn off or on).

This song and video have been made solely for educational purposes. Its level of depth and detail into various macromolecules (biomolecules) are aimed at High School Biology students (at least the ones I teach). If you find errors or omissions (i.e. I didn’t discuss enzymes), this is due to the fact that I’m trying to make a song that appeals to students, AND I’m being constrained by describing a relatively complex topic through a highly repetitive song that was originally written in Korean.

Of course, a big reason for making this video was to perform the dance and film it.

I also performed this song for my students in class before our macromolecule test. If you’re lucky, you might find a video of such a live performance somehwere in the vast internet (quite a few of them were recording me singing and dancing it in class, after all). A powerpoint goes with this, as well, so that the words and education I am trying to get through are more clear.

Lyrics:

Molecules Gone Wild!
Bio Style!

Carbohydrates provide the energy for your life!
The simplest form, like glucose, is known as a monosaccharide
Combine two, and make a larger sugar called disaccharide
The largest is a polysaccharide!

Lipids are the fats!
3 fatty acids with a glycerol make up the fats:
Triglycerides with only single bonds are saturated fats,
But if there’re double bonds they now become unsaturated fats
Don’t eat too much fat!

Monomers build to polymers filled
With C, H, O! Hey!
Molecule’s macro! Hey!

One with HO, other with H, so
Bond and go! Hey!
Release H2O! Hey!

Dehydration Synthesis is underway!!!

Molecules Gone Wild!
Bio Style
Mol-Mol-Mol-Mol Molecules Gone Wild!
Bio Style
Mol-Mol-Mol-Mol Molecules Gone Wild!

Many Polymers-mers-mers-mers:
Molecules Gone Wild!
Many Polymers-mers-mers-mers!

Proteins: the building blocks that make up your whole body
Your skin, your hair, your muscles – need protein to get the hotties!
Break down polypeptide to amino acids in your body
Nitrogen comes to the party!

Nucleic Acids!
The famous one is DNA that’s known by all you kids
With 2 polynucleotide chains linked to make it valid,
Which breaks into single nucleotides when it’s digested;
Phosphorous added!

When you eat food, to get in the mood (to study),
Molecules will flow! Hey!
Straight down your throat! Hey!

Need to break those big polymers, so
Here’s H2O! Hey!
Splits to H and O! Hey!

Hydrolysis is what I just now displayed!!!

Molecules Gone Wild!
Bio Style
Mol-Mol-Mol-Mol Molecules Gone Wild!
Bio Style
Mol-Mol-Mol-Mol Molecules Gone Wild!

Many Polymers-mers-mers-mers:
Molecules Gone Wild!
Many Polymers-mers-mers-mers!

Food deforms
Into its simplest forms!
When you eat it, break it down,
Then it reforms!

Now you’re informed!
So please study more!
Study, Study,
Read your notes and textbook

You know what I’m saying?

Molecules Gone Wild!

Many Polymers-mers-mers-mers:
Molecules Gone Wild!
Many Polymers-mers-mers-mers!

Molecules Gone Wild!

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富 含 抗 氧 化, 人 体 内 必 需 脂 肪 酸, 帮 助 人 脑 和 身 体 排 毒. 古 书 记 载 黑 小 茴 香 除 了 无 法 起 死 回 生, 种 籽 可 做 为 每 种 疾 病 的 治 疗 药 物.

Dr Otto Heinrich Warburg (Germany)
Nobel Prize in Medicine 1931 : Biochemist
The body requires special fats that, among other important functions. make it possible for sufficient oxygen to reach the cells via the cellular membranes. Which are the key, These special fats are highly oxygen-absorbing. Called Essential Fatty Acids, or EFAs, these special fats must be supplied from outside the body every day.

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Contain antioxidant-like phytonutrients including ellagitannins and anthocyanins. These may help fight viruses, inflammation, and a number of other serious health conditions. Antioxidants seek out and eliminate cell-damaging substances, called free radicals. Free radicals can occur naturally in the body or from exposure to environmental toxins. Although ellagitannins exist in most berries, raspberries contain the the most potent levels.

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Grape seeds have an abundant source of flavonoids called proanthocyanidins. This is important for brain health due to their free radical-quenching antioxidant and collagen-protecting effects. Proanthocyanidins have also been shown to noticeably delay the onset of lipid peroxidation and to effectively chelate iron ions. Free iron ions are some of the most powerful promoters of lipid peroxide, hydrogen peroxide and hydroxyl radical production. This is a major contributor to the pathogenesis of Parkinsons disease, one of the most common neurological diseases in older individuals.

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Ribose-D is a five-carbon sugar found in every cell in our bodies that combines with oxygen and ATP (adenosine triphoshate) to give energy to each cell. Ribose is also present in RNA (ribonucleic acid), which is one of the main information carriers of living organisms. Oxidative stress, as measured by free radical damage to cells, leads to systematic inflammation. Fortunately, our bodies handle this problem daily. However, if our bodies experience an abnormal increase in free radicals due to exercise, daily stress, excess smoking, excess saturated fat intake, depressed immune system, aging, etc., the body becomes fatigued and less efficient in producing Ribose-D to replenish cellular energy. Because of this, we need to supplement with Ribose-D in order to regenerate the cells energy system.
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