[Latin Name] Griffonia simplicifolia

[Plant Source] Griffonia Seed

[Specifications] 98%; 99% HPLC

[Appearance] White fine powder

Plant Part Used: Seed

[Particle size] 80 Mesh

[Loss on drying] ≤5.0%

[Heavy Metal] ≤10PPM

[Pesticide residue] EC396-2005, USP 34, EP 8.0, FDA

[Storage] Store in cool & dry area, keep away from the direct light and heat.

[Shelf life] 24 Months

[Package] Packed in paper-drums and two plastic-bags inside.

[Net weight] 25kgs/drum

[What is 5-HTP]

5-HTP (5-Hydroxytryptophan) is a chemical by-product of the protein building block L-tryptophan. It is also produced commercially from the seeds of an African plant known as Griffonia simplicifolia 5-HTP is used for sleep disorders such as insomnia, depression, anxiety, migraine and tension-type headaches, fibromyalgia, obesity, premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), attention deficit-hyperactivity disorder (ADHD), seizure disorder, and Parkinson’s disease.

 [How does it work?]

5-HTP works in the brain and central nervous system by increasing the production of the chemical serotonin. Serotonin can affect sleep, appetite, temperature, sexual behavior, and pain sensation. Since 5-HTP increases the synthesis of serotonin, it is used for several diseases where serotonin is believed to play an important role including depression, insomnia, obesity, and many other conditions.

[Function]

Depression. Some clinical research shows that taking 5-HTP by mouth improve symptoms of depression in some people. Some clinical research shows that taking 5-HTP by mouth might be as beneficial as certain prescription antidepressant drugs for improving depression symptoms. In most studies, 150-800 mg daily of 5-HTP was taken. In some cases, higher doses have been used.

Down syndrome. Some research shows that giving 5-HTP to infants with Down syndrome might improve muscle and activity. Other research shows that it does not improve muscle or development when taken from infancy until 3-4 years of age. Research also shows that taking 5-HTP along with conventional prescription drugs does improve development, social skills, or language skills.

Anxiety 5-HTP was found to be protective against carbon dioxide-induced panic attacks. One study compared 5-HTP and the prescription medication clomipramine for anxiety. Clomipramine is a tricyclic antidepressant used for treating obsessive-compulsive disorder. 5-HTP was found to be somewhat effective in reducing anxiety symptoms, but not as effective as clomipramine.

Sleep 5-HTP supplements fared a little better for insomnia.5-HTP decreased the time required to get to sleep and decreased the number of nighttime awakenings. Taking 5-HTP along with GABA (gamma-aminobutyric acid), a relaxing neurotransmitter, reduced the time it took to fall asleep and increased the duration and quality of sleep. One study found that children with night terrors benefited from 5-HTP.

Poor Blood Circulation, Cold Legs And Hands? Find Out How To Help This!

Body’s circulatory system is the one that carries your blood, oxygen and nutrients every part of body including your vital organs and tissues. You will experience symptoms of poor circulation noticed predominantly in your hands and legs if blood circulation is hampered.

The lifestyles you choice have a big factor on poor circulation, if you’re sitting for long hours of the day then this is probably the reason why. This can be the reason for weak blood vessels and plaque that builds up in the vessels. If you change your lifestyle and exercise more you will improve blood circulation.

Here are some things you should do to improve blood circulation:

Consuming more water

It is necessary to drink at least eight glasses of water each day. It improves your blood flow . Then oxygen and nutrients are carried to your tissues and organs. Moreover it improves your digestion and your cells and tissues are well hydrated. By enhanced physical activity during the day then body wants more than eight glasses of water.

Ginko Biloba– works amazing for improving blood circulation in the brain which will greatly improve your memory. It has also been proven to treat bad blood circulation and also varicose veins. You can find this in pills of capsules.

Cayenne pepper– is rich in capsaicin. It stimulate your heart, strengthens capillaries and arteries. Also clearing any plaque buildup in vessels and same time regulates your blood circulation. It also ease symptoms of inadequate blood circulation as headaches, pain, tingling sensations in your legs ,cold feet and hands.

Garlic– A study has explained how garlic will greatly help people who are suffering with cardiovascular health. To prevent your risk of atherosclerosis, it doesn’t allow plaque to build up in the arteries and will decrease blood pressure.

Horse chestnut-Escin as active compound in horse chestnut strengthen capillary walls. It significantly reduces inflammation. It is known to be used in treating varicose veins and improper blood flow in the body.

Certain essential oils like ginger, thyme and rosemary will give a thermogenic effect to your body and will boost blood flow to the skin and expand capillaries it has also been proven to reduce numbness in the feet hands and will relax tense muscles.

Fish oil-The omega-3 fatty acids build in fish oil help to get rid of fats in arteries and promotes better blood circulation. This oil also improve HDL which is a decent form of cholesterol in the body.

Ginger– If you are the type of person who consumes ginger regularly, you can prevent cardiovascular disease. It contains two active properties gingerols and zingerone which will also warm up the body and increase blood flow.

Video : https://youtu.be/Tb54k9guYJQ

“Equine Polysaccharide Storage Myopathy” is an inheritable glycogen storage disease of horses that causes exertional rhabdomyolysis. It is most commonly associated with heavy horse breeds and the American Quarter Horse. While incurable, PSSM can be managed with appropriate diet and exercise. There are currently 2 subtypes, known as Type 1 PSSM and Type 2 PSSM.

Glycogen is a molecular polymer of glucose used to store energy, and is important for maintaining glucose hemostasis in the blood, as well as for providing energy for skeletal muscle and cardiac muscle contraction. Molecules of glucose are linked into linear chains by α-1,4-glycosidic bonds. Additionally, branches of glucose are formed off of the chain by α-1,6-glycosidic bonds. 2 molecules of glucose are joined into an α-1,4-glycosidic bonds by an enzyme known as glycogen synthase. This bond may be broken by amylase when the body wishes to break down glycogen into glucose for energy. Glycogen branching enzyme is responsible for the required α-1,6-glycosidic bonds needed to start a branch off of these linear chains.

Any disruption to this system results in a glycogen storage disease. There are currently 3 subcategories of glycogen storage diseases in horses: Type 1 Polysaccharide Storage Myopathy, Glycogen Branching Enzyme Deficiency , and Type 2 Polysaccharide Storage Myopathy.

Type 1 PSSM is caused by an autosomal dominant genetic mutation known as GSY1. This mutation causes an up-regulation of glycogen synthase, and high levels of glycogen synthase relative to glycogen branching enzyme . This altered ratio of glycogen synthase to GBE results in glycogen molecules with long chains and few branches, making these molecules somewhat amylase resistant. The GSY1 mutation is associated with altered glucose metabolism , as well as accumulation of high levels of glycogen and abnormal polysaccharide in the muscles of the horse. Additionally, some horses have been shown to have insulin sensitivity, which improves glucose uptake by muscle cells and contributes to excessive glycogen storage that is already elevated secondary to the GSY1 mutation.

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