[Products Name]  Royal jelly powder，Lyophilized royal jelly powder

[Specification]  10-HDA 4.0%, 5.0%, 6.0%, HPLC

[Gerneral feature]

1. Low antibiotics, Chloramphenicol< 0.1ppb

2.Organic certified by ECOCERT, according to EOS & NOP organic standard;

3.100% pure with no additives;

4. More easily absorbed into the body than fresh royal jelly

5. Can be easily produced into tablets.

[Our advantages]

1. 600 bee farmers, 150 units of bee-feeding groups located in natural mountains;
2. Organic certificated by ECOCERT;
3. NON-antibiotics, widely exported to Europe;
4. Health Certificate, Sanitary Certificate and Quality Certificate are available.

[Lyophilized technology]

Lyophilized technology, also known as Freeze-drying, it is a dehydration process typically used to maintain activity of all nutrition ingredients in royal jelly, also to make the royal jelly convenient for transport. Freeze-drying works by freezing the material and then reducing the surrounding pressure to allow the frozen water in the material to sublimate directly from the solid phase to the gas phase. This technology can maintain all activity of nutrition ingredient.

Lyophilized royal jelly powder is processed directly from fresh royal jelly.

3kgs fresh royal jelly is used to make 1kg lyophilized royal jelly powder.

During all the production process, there is no additives.

[Packing]

5kg/bag, 25kgs/drum

1kg/bag, 20kgs/carton

Main indices of physical and chemic in Lyophilized royal jelly

[Our work flow]

Our Lyophilized Royal Jelly Powder is produced in this way: we lyophilize the fresh royal jelly by advanced freeze-drying facilities without losing any nutritional ingredients, reserving the natural ingredients in utmost, and then make them into the form of powder, for any food additives are not needed to add.

The raw material we use is the natural fresh royal jelly which is up to the export standard . We process our products strictly according to export standard. Our workshop is up to the requirements of GMP.

Royal Jelly powder has been selected as drug excipients by many European and American pharmaceutical producing enterprises.Meanwhile it is applies to health food and cosmetics industries.

[Quality control]

Traceability record

GMP standard production

Advanced inspection equipment

[Function]

1.Enhances the immune system

2.Promotes wound healing

3.Has antitumor/anticancer properties

4.Lowers cholesterol levels

5.Increases fat metabolism

6.Is a powerful antioxidant

7.Regulates blood sugar levels

[Applications]

It’s widely used in health tonic, health pharmacy, hairdressing and cosmetic area, and mainly was applied in capsules, troche and oral liquids etc.

Titre du document / Document title
Cytotoxic activity of Justicia spicigera is inhibited by bcl-2 proto-oncogene and induces apoptosis in a cell cycle dependent fashion
Auteur(s) / Author(s)
CACERES-CORTES J. R. (1) ; CANTU-GARZA F. A. (2) ; MENDOZA-MATA M. T. (3) ; CHAVEZ-GONZALEZ M. A. (1) ; RAMOS-MANDUJANO G. (1) ; ZAMBRANO-RAMIREZ I. R. (1) ;
Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)
(1) Research Unit of Cell Differentiation and Cancer, Faculty of Professional Studies-Zaragoza, National Autonomous University of Mexico, FES-Zaragoza, UNAM, MEXIQUE
(2) Chemistry Engineering Department, Faculty of Professional Studies-Zaragoza, National Autonomous University of Mexico, FES-Zaragoza, UNAM, ESPAGNE
(3) Pharmacology Department, Faculty of Professional Studies-Zaragoza, National Autonomous University of Mexico, FES-Zaragoza, UNAM, ESPAGNE

Résumé / Abstract
Identification of organic compounds from plants is of clinical significance because of the effect that they might have in patients with haematopoietic disorders. We studied the effect of the plant extract Justicia spicigera (Acanthaceae) in different haematopoietic cells: human leukaemic cell lines, umbilical cord blood cells, and mouse bone marrow cells. By examining colony formation and performing the MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide) assay it was shown that the plant extract of Justicia spicigera contains cytotoxic factors for leukaemic cells and has no proliferative activity on normal haematopoietic progenitor cells. Our results show that this plant extract induces apoptosis in the human leukaemia cell line TF-1, but not in the bcl-2 transfectant cell line TB-1. Similar results were obtained using a haemopoietic cell line 32D and 32DBcl2. The cultures of umbilical cord blood cells and mouse bone marrow that contain granulocyte-macrophage colony-stimulating factor (GM-CSF) do not proliferate or become terminally differentiated in the presence of the infusion of Justicia spicigera. GM-CSF that acts by abrogating programmed cell death is not sufficient to inhibit the apoptotic stimulus in TF-1 and 32D cells. Moreover mouse fibroblasts (3T3) and two cervical carcinoma cell lines CALO and INBL, undergo apoptosis in the presence of different concentrations of an infusion from the plant. Our data show that there is a strong correlation between the cytotoxic effect and cell proliferation. Together, these results indicate that the plant infusion of Justicia spicigera does not contain any haematopoietic activity, induces apoptosis inhibited by bcl-2 and is linked to cell proliferation.
Revue / Journal Title
PTR. Phytotherapy research ISSN 0951-418X
Source / Source
2001, vol. 15, no8, pp. 691-697 (24 ref.)
Langue / Language
Anglais

Editeur / Publisher
Wiley, Chichester, ROYAUME-UNI (1987) (Revue)

Mots-clés anglais / English Keywords
America ; Central America ; Spermatophyta ; Angiospermae ; Dicotyledones ; Acanthaceae ; Mexico ; Folk medicine ; Pharmacognosy ; Animal ; Human ; Apoptosis ; In vitro ; Cell proliferation ; Antineoplastic agent ; Tumor cell ; Biological activity ; Cytotoxicity ; Plant origin ; Medicinal plant ;

•Combats free radicals•Demonstrates anti-inflammatory activity•Helps maintain healthy cholesterol levels•Helps maintain healthy circulation•Supports healthy blood glucose levels
•And more….